Is late-follicular phase progesterone rise associated with a deleterious on embryo quality?

Previous studies have shown that late follicular phase progesterone elevation may adversely affect pregnancy outcomes in IVF/ICSI cycles. Although most of the studies supported a potential detrimental effect of progesterone elevation on implantation rates, recent reports support a potential detrimental effect of progesterone elevation on embryo quality.
N. P. Polyzos, S. Garcia-Martinez, I. Rodriguez, P. Montoya-Botero, F. Martinez, P. Barri, B. Coroleu.
Dexeus University Hospital, Reproductive Medicine Department, Barcelona, Spain.