Is late-follicular phase progesterone rise associated with a deleterious on embryo quality?

Is late-follicular phase progesterone rise associated with a deleterious on embryo quality?

Previous studies have shown that late follicular phase progesterone elevation may adversely affect pregnancy outcomes in IVF/ICSI cycles. Although most of the studies supported a potential detrimental effect of progesterone elevation on implantation rates, recent reports support a potential detrimental effect of progesterone elevation on embryo quality.

POSTER: Late-follicular phase progesterone rise does not affect embryo euploidy and cumulative live birth rates. An analysis of 1500 embryos following PGT-A

N. P. Polyzos, S. Garcia-Martinez, I. Rodriguez, P. Montoya-Botero, F. Martinez, P. Barri, B. Coroleu.
Dexeus University Hospital, Reproductive Medicine Department, Barcelona, Spain.